- 2019 Uni High Scholastic Bowl team won first place at the National Academic Quiz Tournament State Championship (NAQT).
- 2018 Uni High Scholastic Bowl team won first place at the National Academic Quiz Tournament State Championship (NAQT).
- 2018 Arielle Summitt made the IHSA 2017-18 All-State Academic Team.
- 2017 Annemarie Michael made the IHSA 2016-17 All-State Academic Team.
- 2016 Uni High students Sarah Zhang, Joy Chen, Aditya Yedetore, Rima Rebei, and Katie Tender won the national ExploraVision competition for their project "BEISight: Bionic Eye Implant for Sight".
- 2015 Uni High Scholastic Bowl team won first place at state.
- 2015 Uni graduate Rachel Harmon received Rhodes Scholarship